EFFICACY OF AZITHROMYCIN ON EXPERIMENTAL TOXOPLASMOSIS INFECTED MICE
نویسندگان
چکیده
منابع مشابه
Toxoplasmosis in Experimentally Infected Mice
Acute and chronic Toxoplasma infections were evaluated in mice using stage specific antibodies and immunocytochemistry. Mice with acute toxoplasmosis were less active, had erectile body hair and seldom took food or water resulting in weight loss. All mice died within 7 days post-inoculation. The immunohistochemical technique enhanced visualization of parasites allowing their distribution to be ...
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AIMS To investigate the efficacy of azithromycin in patients with ocular toxoplasmosis. METHODS 11 immunocompetent patients with ocular toxoplasmosis were treated with azithromycin (500 mg the first day, followed by 250 mg/day for 5 weeks). Ocular and systemic examinations were performed during active retinitis episodes and all patients were followed for at least 1 year. RESULTS The intraoc...
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The hypothesis, that hypoiodemia of goats causes such a compromise of the immune system, which during subsequent Toxoplasma gondii infections results in clinically more pronounced signs of toxoplasmosis, was verifying in laboratory mouse. Hypoiodemic mice (fed by wheat and supplied by water), normoiodemic mice (fed by wheat and supplied by water containing 1.25 mg KI/l) and the majority of stan...
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Background: Toxoplasma gondii is an obligate intracellular parasite that infects all mammalian cells. Several antigens such as excreted/secreted antigens have been identified as a potential vaccine candidate. Objective: To determine how excreted/secreted antigens from peritoneal exudates of infected mice (mESA) stimulate cell-mediated immune responses and induce protective immunity against toxo...
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Background and Objectives: Considering the resistance of the Plasmodium parasite (the causative agent of Malaria) to antimalarial drugs, it is essential to find an alternative medicine for treating patients. Therefore, the present study aimed to investigate the antimalarial effect of Zingiber Officinale hydroalcoholic extract on mice infected with Plasmodium berghei. Materials and Methods: In ...
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ژورنال
عنوان ژورنال: Journal of the Egyptian Society of Parasitology
سال: 2020
ISSN: 2090-2549
DOI: 10.21608/jesp.2020.113050